About the Authors

Paul W. Fenimore

paulf@lanl.gov

Affiliation Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

Majidat A. Muhammad

Contributed equally to this work with: Majidat A. Muhammad, William M. Fischer

Affiliation Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fredrick, Maryland, United States of America

William M. Fischer

Contributed equally to this work with: Majidat A. Muhammad, William M. Fischer

Affiliation Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

Brian T. Foley

Affiliation Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

Russell R. Bakken

Affiliation Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fredrick, Maryland, United States of America

James R. Thurmond

Affiliation Fly Base, Indiana University, Bloomington, Indiana, United States of America

Karina Yusim

Affiliation Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

Hyejin Yoon

Affiliation Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

Michael Parker

Affiliation Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fredrick, Maryland, United States of America

Mary Kate Hart

Affiliation DynPort Vaccine Company, Frederick, Maryland, United States of America

John M. Dye

Affiliation Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fredrick, Maryland, United States of America

Bette Korber

Affiliation Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

Carla Kuiken

Affiliation Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflicts. Co-author M.K. Hart is an employee of DynPort Vaccine Company, a private company engaged in vaccine production. P.W. Fenimore, W. Fischer, C. Kuiken, and B.T. Korber have a patent interest in the work described. The patent disclosure is DOE S129405 entitled “Mosaic Protein Antigens for a Pan-Filoviral Vaccine”, US Patent Application Number 61/623,342 filed 4/12/2012. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. The authors' adherence is demonstrated by inclusion of patent-sensitive data in one supplementary information file, and the specification of all input data for the authors' analysis. This study is reproducible from the information in the manuscript, figures, and supporting information.

Author Contributions

Mosaic optimization: PWF. Conceived and designed the experiments: PWF MAM WMF BTF RB JRT KY HY MP MKH JD BK CK. Performed the experiments: MAM RB JD. Analyzed the data: PWF WMF BTF JRT KY HY JD BK CK. Contributed reagents/materials/analysis tools: PWF WMF MAM BTF RB JRT KY HY JD MP MKH BK CK. Wrote the paper: PWF WMF CK BK JD.