About the Authors
- Maria Beconi
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Affiliation CHDI Management/CHDI Foundation Inc., Los Angeles, California, United States of America
- Omar Aziz
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Affiliation BioFocus, Saffron Walden, Essex, United Kingdom
- Kim Matthews
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Affiliation BioFocus, Saffron Walden, Essex, United Kingdom
- Lara Moumné
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Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
- Catherine O’Connell
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Affiliation BioFocus, Saffron Walden, Essex, United Kingdom
- Dawn Yates
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Affiliation BioFocus, Saffron Walden, Essex, United Kingdom
- Steven Clifton
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Affiliation BioFocus, Saffron Walden, Essex, United Kingdom
- Hannah Pett
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Affiliation BioFocus, Saffron Walden, Essex, United Kingdom
- Julie Vann
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Affiliation BioFocus, Saffron Walden, Essex, United Kingdom
- Lynsey Crowley
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Affiliation BioFocus, Saffron Walden, Essex, United Kingdom
- Alan F. Haughan
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Affiliation BioFocus, Saffron Walden, Essex, United Kingdom
- Donna L. Smith
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Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
- Ben Woodman
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Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
- Gillian P. Bates
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Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
- Fred Brookfield
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Affiliation Evotec (UK) Ltd., Abingdon, United Kingdom
- Roland W. Bürli
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Affiliation BioFocus, Saffron Walden, Essex, United Kingdom
- George McAllister
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Affiliation BioFocus, Saffron Walden, Essex, United Kingdom
- Celia Dominguez
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Affiliation CHDI Management/CHDI Foundation Inc., Los Angeles, California, United States of America
- Ignacio Munoz-Sanjuan
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Affiliation CHDI Management/CHDI Foundation Inc., Los Angeles, California, United States of America
- Vahri Beaumont
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* E-mail: vahri.beaumont@chdifoundation.org
Affiliation CHDI Management/CHDI Foundation Inc., Los Angeles, California, United States of America
Competing Interests
The authors have declared that no competing interests exist. CHDI Foundation is a not-for-profit biomedical research organization exclusively dedicated to discovering and developing therapeutics that slow the progression of Huntington’s disease. Evotec (UK) and BioFocus (UK) conducted the research through a fee-for-service agreement for CHDI Foundation. This declaration does not alter the authors’ adherence to all PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: MB OA KM LM DY GPB CD IMS RWB GM VB. Performed the experiments: OA KM LM COC SC HP JV LC AFH DLS BW FB. Analyzed the data: OA KM MB DY LM COC SC HP JV FB GPB VB. Contributed reagents/materials/analysis tools: FB. Wrote the paper: MB VB.