About the Authors

William H. Thiel

Affiliation Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America

Thomas Bair

Affiliation Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America

Andrew S. Peek

Affiliation Roche Molecular Systems, San Francisco, California, United States of America

Xiuying Liu

Affiliation Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America

Justin Dassie

Affiliation Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America

Katie R. Stockdale

Affiliation Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America

Mark A. Behlke

Affiliation Integrated DNA Technologies, Coralville, Iowa, United States of America

Francis J. Miller Jr

Affiliation Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America

Paloma H. Giangrande

paloma-giangrande@uiowa.edu

Affiliations Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America, Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, United States of America

Competing Interests

MAB is currently employed by Integrated DNA Technologies, Inc. (IDT). ASP was employed by IDT at the time the work described in the manuscript was performed. IDT offers oligonucleotides for sale and is not a publicly traded company. Neither author owns any shares/equity in IDT. MAB is on the scientific advisory board of Dicerna Pharmaceuticals. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: WHT ASP MAB FJM PHG. Performed the experiments: WHT TB XL JD. Analyzed the data: WHT FJM PHG. Contributed reagents/materials/analysis tools: WHT FJM PHG KRS. Wrote the paper: WHT PHG.