About the Authors

Maria A. Cantu

Affiliation Baylor College of Medicine, Houston, Texas, United States of America

Philip J. Lupo

Affiliation Division of Epidemiology, University of Texas School of Public Health, Houston, Texas, United States of America

Mrinalini Bilgi

Affiliation Texas Children’s Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas, United States of America

M. John Hicks

Affiliation Department of Pathology, Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas, United States of America

Carl E. Allen

Affiliation Texas Children’s Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas, United States of America

Kenneth L. McClain

klmcclai@txch.org

Affiliation Texas Children’s Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas, United States of America

Competing Interests

K. McClain owns common stock in the Johnson and Johnson Company, has research support from the National Institutes of Health, and clinical trial support from the Glaxo Smith Kline Company. C. Allen has research support for the National Institutes of Health and clinical trial support from the Glaxo Smith Kline Company. The other authors have no conflicts to report. The above is funding unrelated to this study. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials, as detailed online on the guide for authors.

Author Contributions

Conceived and designed the experiments: PJL CEA KLM. Performed the experiments: KLM. Analyzed the data: MAC PJL MB MJH CEA KLM. Contributed reagents/materials/analysis tools: PJL MB. Wrote the paper: MAC PJL CEA KLM.