About the Authors
- Theodore G. Liou
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* E-mail: ted.liou@utah.edu
Affiliations Department of Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United States of America, Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah, United States of America, Intermountain Adult CF Center, University of Utah, Salt Lake City, Utah, United States of America
- Frederick R. Adler
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Affiliations Department of Mathematics, University of Utah, Salt Lake City, Utah, United States of America, Department of Biology, University of Utah, Salt Lake City, Utah, United States of America
- Ruth H. Keogh
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Affiliation Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, United Kingdom
- Yanping Li
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Affiliations Department of Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United States of America, Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah, United States of America, Intermountain Adult CF Center, University of Utah, Salt Lake City, Utah, United States of America
- Judy L. Jensen
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Affiliations Department of Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United States of America, Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah, United States of America, Intermountain Adult CF Center, University of Utah, Salt Lake City, Utah, United States of America
- William Walsh
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Affiliations Department of Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United States of America, Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah, United States of America, Intermountain Adult CF Center, University of Utah, Salt Lake City, Utah, United States of America
- Kristyn Packer
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Affiliations Department of Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United States of America, Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah, United States of America, Intermountain Adult CF Center, University of Utah, Salt Lake City, Utah, United States of America
- Teresa Clark
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Affiliation Intermountain Adult CF Center, University of Utah, Salt Lake City, Utah, United States of America
- Holly Carveth
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Affiliations Department of Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United States of America, Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah, United States of America, Intermountain Adult CF Center, University of Utah, Salt Lake City, Utah, United States of America
- Jun Chen
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Current address: Johnson & Johnson Pharmaceutical Research and Development, LLC, Spring House, Pennsylvania, United States of America
Affiliations Department of Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United States of America, Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah, United States of America, Intermountain Adult CF Center, University of Utah, Salt Lake City, Utah, United States of America
- Shaunessy L. Rogers
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Current address: Department of Medicine, Oregon Health and Science University, Portland, Oregon, United States of America
Affiliations Department of Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United States of America, Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah, United States of America, Intermountain Adult CF Center, University of Utah, Salt Lake City, Utah, United States of America
- Christen Lane
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Affiliations Department of Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United States of America, Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah, United States of America, Intermountain Adult CF Center, University of Utah, Salt Lake City, Utah, United States of America
- James Moore
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Affiliation Department of Mathematics, University of Utah, Salt Lake City, Utah, United States of America
- Anne Sturrock
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Affiliations Department of Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United States of America, Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah, United States of America
- Robert Paine III
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Affiliations Department of Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United States of America, Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah, United States of America
- David R. Cox
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Affiliation Department of Statistics and Nuffield College, Oxford, United Kingdom
- John R. Hoidal
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Affiliation Department of Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, United States of America
Competing Interests
The authors have read the journal’s policy and have the following conflicts: TGL is a member of the/Chest/Editorial Board, the CF Foundation Clinical Research Grant Review Committee and is a recent past member of the CF Foundation Patient Registry Data Use Review Committee and the Lung Sub-committee of the United Network for Organ Sharing Thoracic Board. As principal investigator on a Therapeutic Development Network Center Grant from the CF Foundation, TGL has been principal investigator on clinical studies for Altus, Axcan-Scandipharm, Bayer, Boehringer Ingelheim, Genentech, Inspire, Kalobios, MPEX, Novartis, and Vertex. TGL has received honoraria from Actelion for service as a consultant to the Steering Committee for the Registry to Evaluate Early and Long Term PAH Disease Management project studying pulmonary arterial hypertension, and he has received honoraria as a consultant on CF for Genentech, Gehrson-Lehman and Vertex. TGL has provided expert legal testimony. These affiliations do not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials. As co-investigator on a Therapeutic Development Network Center Grant from the CF Foundation, HC has been an investigator for studies of CF and its treatment for Altus, Axcan-Scandipharm, Bayer, Boehringer-Ingelheim, Genentech, Inspire, Kalobios, MPEX, Novartis, and Vertex. These affiliations do not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials. JC is currently a contractor for Johnson and Johnson. Her work on this project occurred while she was at the University of Utah. Recent work on writing and editing the manuscript was done on her own time and was not connected in any way with her current contract. This affiliation does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials. RP has a pending grant proposal to the Department of Veterans Affairs to study the biology of GM-CSF in the pulmonary alveolar space. This affiliation does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: TGL FRA JM RP JRH. Performed the experiments: TGL YL JLJ WW KP TC HC JC SLR CL AS. Analyzed the data: TGL FRA RHK WW JM RP DRC JRH. Contributed reagents/materials/analysis tools: TGL FRA RHK WW DRC. Wrote the paper: TGL FRA RHK WW JRH DRC.