About the Authors
- Wenxue Ma
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- Alejandro Gutierrez
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Affiliation Department of Pediatric Oncology, Dana-Farber Cancer Institute and Children’s Hospital Boston, Boston, Massachusetts, United States of America
- Daniel J. Goff
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- Ifat Geron
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- Anil Sadarangani
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- Christina A. M. Jamieson
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- Angela C. Court
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- Alice Y. Shih
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- Qingfei Jiang
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- Christina C. Wu
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- Kang Li
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Affiliation Oncology Research Unit, Pfizer Global Research and Development, La Jolla Laboratories, San Diego, California, United States of America
- Kristen M. Smith
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- Leslie A. Crews
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- Neil W. Gibson
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Affiliation Oncology Research Unit, Pfizer Global Research and Development, La Jolla Laboratories, San Diego, California, United States of America
- Ida Deichaite
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- Sheldon R. Morris
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- Ping Wei
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Affiliation Oncology Research Unit, Pfizer Global Research and Development, La Jolla Laboratories, San Diego, California, United States of America
- Dennis A. Carson
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Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
- A. Thomas Look
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Affiliation Department of Pediatric Oncology, Dana-Farber Cancer Institute and Children’s Hospital Boston, Boston, Massachusetts, United States of America
- Catriona H. M. Jamieson
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* E-mail: cjamieson@ucsd.edu
Affiliation Department of Medicine, Stem Cell Program and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
Competing Interests
A portion of this research study was funded by a sponsored research agreement with Pfizer (Pfizer/28-1076), and the antibody utilized in this study was provided by Pfizer. K. Li and N. Gibson were employees of Pfizer while engaged in the research project. P. Wei is an employee of Pfizer and owns stock in the company. This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials. Authors W. Ma, D.J. Goff, I. Geron, A. Sadarangani, C.A.M. Jamieson, A. Court, A. Shih, Q. Jiang, C. Wu, K. Smith, L.A. Crews, I. Deichaite, S. Morris, and D. Carson declare no potential conflicts of interest.
Author Contributions
Conceived and designed the experiments: WM DAC ATL CHMJ. Performed the experiments: WM AG DJG IG AS CAMJ ACC AYS QJ CCW KMS PW. Analyzed the data: WM CAMJ KMS LAC SRM ATL DAC CHMJ. Contributed reagents/materials/analysis tools: KL PW NWG. Wrote the paper: WM LAC DAC ATL CHMJ. Obtained permission for use of the Pfizer antibody: ID. Accept direct responsibility for the manuscript: WM CHJM.