About the Authors

Pia K. Schuler

Contributed equally to this work with: Pia K. Schuler, Laurent M. Haegeli

Affiliations Clinic for Cardiology, Cardiovascular Center, University Hospital of Zurich, Zurich, Switzerland, Adult Congenital and Valvular Heart Disease Center, Department of Cardiology and Angiology, University Hospital Muenster, Muenster, Germany

Laurent M. Haegeli

Contributed equally to this work with: Pia K. Schuler, Laurent M. Haegeli

laurent.haegeli@usz.ch

Affiliation Clinic for Cardiology, Cardiovascular Center, University Hospital of Zurich, Zurich, Switzerland

Ardan M. Saguner

Affiliation Clinic for Cardiology, Cardiovascular Center, University Hospital of Zurich, Zurich, Switzerland

Thomas Wolber

Affiliations Clinic for Cardiology, Cardiovascular Center, University Hospital of Zurich, Zurich, Switzerland, Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland

Felix C. Tanner

Affiliations Clinic for Cardiology, Cardiovascular Center, University Hospital of Zurich, Zurich, Switzerland, Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland

Rolf Jenni

Affiliations Clinic for Cardiology, Cardiovascular Center, University Hospital of Zurich, Zurich, Switzerland, Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland

Natascia Corti

Affiliation Division of Clinical Pharmacology and Toxicology, University Hospital of Zurich, Zurich, Switzerland

Thomas F. Lüscher

Affiliations Clinic for Cardiology, Cardiovascular Center, University Hospital of Zurich, Zurich, Switzerland, Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland

Corinna Brunckhorst

Affiliation Clinic for Cardiology, Cardiovascular Center, University Hospital of Zurich, Zurich, Switzerland

Firat Duru

Affiliations Clinic for Cardiology, Cardiovascular Center, University Hospital of Zurich, Zurich, Switzerland, Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland

Competing Interests

There are no conflicts of interest involved other than research grants to the institution from Medtronic, Biotronik, St. Jude and Boston Scientific not directly related to this project. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: PS FD. Analyzed the data: PS CB FT RJ TL FD. Wrote the paper: PS LH AS TW CB NC. Data acquisition, statistics: PS.