About the Authors

Nesrin Sabha

Affiliation Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children Research Institute, University of Toronto, Toronto, Canada

Karolyn Au

Affiliation Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children Research Institute, University of Toronto, Toronto, Canada

Sameer Agnihotri

Affiliation Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children Research Institute, University of Toronto, Toronto, Canada

Sanjay Singh

Affiliation Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children Research Institute, University of Toronto, Toronto, Canada

Rupinder Mangat

Affiliation Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children Research Institute, University of Toronto, Toronto, Canada

Abhijit Guha

Affiliations Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children Research Institute, University of Toronto, Toronto, Canada, Department of Surgery (Neurosurgery), Western Hospital, University of Toronto, Toronto, Canada

Gelareh Zadeh

Gelareh.Zadeh@uhn.on.ca

Affiliations Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children Research Institute, University of Toronto, Toronto, Canada, Department of Surgery (Neurosurgery), Western Hospital, University of Toronto, Toronto, Canada

Competing Interests

The authors have the following interests to declare: Novartis provided Nilotinib and partial funding for this study. There are no patents, products in development or marked products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: NS AG GZ. Performed the experiments: NS. Analyzed the data: NS. Contributed reagents/materials/analysis tools: KA SA SS RM. Wrote the paper: NS KA AG GZ.