About the Authors

Lele Hu

Contributed equally to this work with: Lele Hu, Weiren Cui

Affiliations Institute of Systems Biology, Shanghai University, Shanghai, People’s Republic of China, Department of Chemistry, College of Sciences, Shanghai University, Shanghai, People’s Republic of China

Weiren Cui

Contributed equally to this work with: Lele Hu, Weiren Cui

Affiliation CAS-MPG Partner Institute of Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People’s Republic of China

Zhisong He

Affiliation CAS-MPG Partner Institute of Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People’s Republic of China

Xiaohe Shi

Affiliation Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China

Kaiyan Feng

Affiliation Shanghai Center for Bioinformation Technology, Shanghai, China

Buyong Ma

mabuyong@mail.nih.gov (BM); cai_yud@yahoo.com.cn (YDC)

Affiliation Basic Science Program, SAIC – Frederick, Center for Cancer Research Nanobiology Program, National Cancer Institute-Fredeick, National Institute of Health, Frederick, Maryland, United States of America

Yu-Dong Cai

mabuyong@mail.nih.gov (BM); cai_yud@yahoo.com.cn (YDC)

Affiliation Institute of Systems Biology, Shanghai University, Shanghai, People’s Republic of China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YDC BM. Performed the experiments: LH WC ZH. Analyzed the data: YDC BM XS KF. Contributed reagents/materials/analysis tools: YDC BM LH WC. Wrote the paper: YDC BM LH WC KF.