About the Authors

Christel Krueger

christel.krueger@babraham.ac.uk (CK); wolf.reik@bbsrc.ac.uk (WR)

Affiliation Epigenetics Programme, The Babraham Institute, Cambridge, United Kingdom

Michelle R. King

Affiliation Epigenetics Programme, The Babraham Institute, Cambridge, United Kingdom

Felix Krueger

Affiliation Bioinformatics Group, The Babraham Institute, Cambridge, United Kingdom

Miguel R. Branco

Current address: Epigenetics Programme, The Babraham Institute, Cambridge, United Kingdom; Centre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom

Affiliation Genome Function Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, London, United Kingdom

Cameron S. Osborne

Affiliation Nuclear Dynamics Programme, The Babraham Institute, Cambridge, United Kingdom

Kathy K. Niakan

Affiliations Centre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom, Anne McLaren Laboratory for Regenerative Medicine, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom

Michael J. Higgins

Affiliation Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, New York, United States of America

Wolf Reik

christel.krueger@babraham.ac.uk (CK); wolf.reik@bbsrc.ac.uk (WR)

Affiliations Epigenetics Programme, The Babraham Institute, Cambridge, United Kingdom, Centre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Performed bioinformatic analysis: FK. Developed allele-specific 4C-Seq: CK CSO. Developed computational model: MRB. Directed the study: WR. Conceived and designed the experiments: CK MRK. Performed the experiments: CK MRK. Analyzed the data: CK MRK. Contributed reagents/materials/analysis tools: KKN MJH. Wrote the paper: CK.