Krüppel-Like Factor 5 Protects against Murine Colitis and Activates JAK-STAT Signaling In Vivo

Marie-Pier Tetreault; Rami Alrabaa; Megan McGeehan; Jonathan P. Katz

doi:10.1371/journal.pone.0038338

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Open Access

Peer-reviewed

Research Article

Krüppel-Like Factor 5 Protects against Murine Colitis and Activates JAK-STAT Signaling In Vivo

Marie-Pier Tetreault,

Affiliation Division of Gastroenterology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Rami Alrabaa,

Affiliation Division of Gastroenterology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Megan McGeehan,

Affiliation Division of Gastroenterology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Jonathan P. Katz

* E-mail: jpkatz@mail.med.upenn.edu

Affiliation Division of Gastroenterology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯

Krüppel-Like Factor 5 Protects against Murine Colitis and Activates JAK-STAT Signaling In Vivo

Marie-Pier Tetreault,
Rami Alrabaa,
Megan McGeehan,
Jonathan P. Katz

Published: May 31, 2012
https://doi.org/10.1371/journal.pone.0038338

About the Authors

Marie-Pier Tetreault

Affiliation Division of Gastroenterology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

Rami Alrabaa

Affiliation Division of Gastroenterology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

Megan McGeehan

Affiliation Division of Gastroenterology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

Jonathan P. Katz

* E-mail: jpkatz@mail.med.upenn.edu

Affiliation Division of Gastroenterology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MT JPK. Performed the experiments: MT RA MM. Analyzed the data: MT RA MM JPK. Wrote the paper: MT JPK. Obtained funding for the experiments: JPK.

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Gastrointestinal tract
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Colon
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Colitis
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Epithelial cells
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Genetically modified animals
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Inflammatory bowel disease
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STAT signaling
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Phosphorylation
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