About the Authors

Lina Zgaga

lina.zgaga@ed.ac.uk (LZ); harry.campbell@ed.ac.uk (HC)

Affiliations Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom, Andrija Stampar School of Public Health, Medical School, University of Zagreb, Zagreb, Croatia

Evropi Theodoratou

Affiliations Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom, Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh and MRC Human Genetics Unit Western General Hospital, Edinburgh, United Kingdom

Janet Kyle

Affiliation Public Health Nutrition Research Group, The Rowett Institute of Nutrition and Health, Greenburn Road, Bucksburn, Aberdeen, United Kingdom

Susan M. Farrington

Affiliation Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh and MRC Human Genetics Unit Western General Hospital, Edinburgh, United Kingdom

Felix Agakov

Affiliations Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom, Pharmatics Limited, Edinburgh, United Kingdom

Albert Tenesa

Affiliation Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh and MRC Human Genetics Unit Western General Hospital, Edinburgh, United Kingdom

Marion Walker

Affiliation Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh and MRC Human Genetics Unit Western General Hospital, Edinburgh, United Kingdom

Geraldine McNeill

Affiliation Public Health Nutrition Research Group, The Rowett Institute of Nutrition and Health, Greenburn Road, Bucksburn, Aberdeen, United Kingdom

Alan F. Wright

Affiliation MRC Human Genetics Unit; Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, Scotland, United Kingdom

Igor Rudan

Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

Malcolm G. Dunlop

Affiliation Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh and MRC Human Genetics Unit Western General Hospital, Edinburgh, United Kingdom

Harry Campbell

lina.zgaga@ed.ac.uk (LZ); harry.campbell@ed.ac.uk (HC)

Affiliations Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom, Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh and MRC Human Genetics Unit Western General Hospital, Edinburgh, United Kingdom

Competing Interests

The authors have the following interest. Felix Agakov is employed by Pharmatics Limited. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: LZ HC IR. Performed the experiments: JK SMF MW GM. Analyzed the data: LZ FA ET JK AT. Wrote the paper: LZ HC ET. Provided significant advice and consultation: HC JK AFW IR MGD.