About the Authors

Weiwei Huang

Contributed equally to this work with: Weiwei Huang, Tiantian He

Affiliation Key Laboratory of Agricultural Molecular Biology, College of Life Science, Northwest A&F University, Yangling, Shaanxi Province, People's Republic of China

Tiantian He

Contributed equally to this work with: Weiwei Huang, Tiantian He

Affiliations Key Laboratory of Agricultural Molecular Biology, College of Life Science, Northwest A&F University, Yangling, Shaanxi Province, People's Republic of China, UMR3348 Centre National de la Recherche Scientifique, Institut Curie, Université Paris-Sud 11, Orsay, France

Chengsen Chai

Affiliation Key Laboratory of Agricultural Molecular Biology, College of Life Science, Northwest A&F University, Yangling, Shaanxi Province, People's Republic of China

Yuan Yang

Affiliation Key Laboratory of Agricultural Molecular Biology, College of Life Science, Northwest A&F University, Yangling, Shaanxi Province, People's Republic of China

Yahong Zheng

Affiliation Key Laboratory of Agricultural Molecular Biology, College of Life Science, Northwest A&F University, Yangling, Shaanxi Province, People's Republic of China

Pei Zhou

Affiliation Key Laboratory of Agricultural Molecular Biology, College of Life Science, Northwest A&F University, Yangling, Shaanxi Province, People's Republic of China

Xiaoxia Qiao

Affiliation Key Laboratory of Agricultural Molecular Biology, College of Life Science, Northwest A&F University, Yangling, Shaanxi Province, People's Republic of China

Bin Zhang

Affiliation Key Laboratory of Agricultural Molecular Biology, College of Life Science, Northwest A&F University, Yangling, Shaanxi Province, People's Republic of China

Zengzhen Liu

Affiliation Key Laboratory of Agricultural Molecular Biology, College of Life Science, Northwest A&F University, Yangling, Shaanxi Province, People's Republic of China

Junru Wang

Affiliation Key Laboratory of Agricultural Molecular Biology, College of Life Science, Northwest A&F University, Yangling, Shaanxi Province, People's Republic of China

Changhong Shi

Affiliation State Key laboratory of Tumor Biology, The Fourth Military Medical University, Xi'an, Shaanxi Province, People's Republic of China

Liping Lei

Affiliation Xi'an San-Yao Bio-pharmaceutical Corporation, Xi'an, Shaanxi Province, People's Republic of China

Kun Gao

Affiliation State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, Gansu Province, People's Republic of China

Hewei Li

Affiliation School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, People's Republic of China

Sue Zhong

Affiliation Xi'an San-Yao Bio-pharmaceutical Corporation, Xi'an, Shaanxi Province, People's Republic of China

Libo Yao

Affiliation State Key laboratory of Tumor Biology, The Fourth Military Medical University, Xi'an, Shaanxi Province, People's Republic of China

Meng-Er Huang

Affiliation UMR3348 Centre National de la Recherche Scientifique, Institut Curie, Université Paris-Sud 11, Orsay, France

Ming Lei

leiming70@hotmail.com

Affiliation Key Laboratory of Agricultural Molecular Biology, College of Life Science, Northwest A&F University, Yangling, Shaanxi Province, People's Republic of China

Competing Interests

The authors have declared that no competing interests exist, although two co-authors are from a commercial company (Bio-pharmaceutical Corporation) who contributed some reagents or analysis tools for the experiments involved in this paper. The company also has no financial or non-financial competing interests exist. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: ML MEH WH TH. Performed the experiments: WH TH CC YY PZ XQ ZL YZ BZ. Analyzed the data: ML WH TH CC PZ XQ. Contributed reagents/materials/analysis tools: JW LL CS HL KG SZ LY. Wrote the paper: WH TH MEH ML.