About the Authors

Peng Qiu

pqiu@mdanderson.org

Affiliation Department of Bioinformatics and Computational Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Competing Interests

One of the three main computational components in this paper is the SPADE algorithm. PQ is on a patent for the SPADE algorithm, which has been applied for on behalf of Stanford University. This does not alter the author's adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: PQ. Performed the experiments: PQ. Analyzed the data: PQ. Contributed reagents/materials/analysis tools: PQ. Wrote the paper: PQ. Designed the software used in analysis: PQ.