About the Authors

Julie K. Hurt

Affiliation Department of Cell and Molecular Physiology, Neuroscience Center, University of North Carolina, Chapel Hill, North Carolina, United States of America

Brendan J. Fitzpatrick

Affiliation Department of Cell and Molecular Physiology, Neuroscience Center, University of North Carolina, Chapel Hill, North Carolina, United States of America

Jacqueline Norris-Drouin

Affiliation Center for Integrative Chemical Biology and Drug Discovery, University of North Carolina, Chapel Hill, North Carolina, United States of America

Mark J. Zylka

zylka@med.unc.edu

Affiliation Department of Cell and Molecular Physiology, Neuroscience Center, University of North Carolina, Chapel Hill, North Carolina, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflict: MJZ is listed as an inventor on a patent application that was licensed for the purpose of developing PAP as a treatment for pain. Patent details: Zylka, M.J. and Vihko, P. Prostatic acid phosphatase for the treatment of pain, U.S. Provisional patent SN# 61/003,205, filed Nov 15, 2007 to US Patent office. Full U.S. patent # 12/743,110 filed May 14, 2010. Zylka, M.J. and Vihko, P. Prostatic acid phosphatase for the treatment of pain, International Application # PCT/US08/12849. The corresponding author provides free advice/consultation to the commercial entity that licensed the patent. In other words, MJZ is not financially compensated for his time. These competing interests do not alter the authors' adherence to all PLoS ONE policies on sharing materials, methods, and data. The authors are free to share everything described in this submitted manuscript.

Author Contributions

Conceived and designed the experiments: JKH MJZ. Performed the experiments: JKH BJF JND. Analyzed the data: JKH MJZ. Contributed reagents/materials/analysis tools: JKH JND. Wrote the paper: JKH MJZ.