About the Authors

Julie H. Levison

jlevison@partners.org

Affiliations Division of General Medicine Massachusetts General Hospital, Boston, Massachusetts, United States of America, Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Catherine Orrell

Contributed equally to this work with: Catherine Orrell, Sébastien Gallien

Affiliation Department of Medicine, Desmond Tutu HIV Center, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa

Sébastien Gallien

Contributed equally to this work with: Catherine Orrell, Sébastien Gallien

Affiliations Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard University Center for AIDS Research, Harvard University, Boston, Massachusetts, United States of America

Daniel R. Kuritzkes

Affiliations Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard University Center for AIDS Research, Harvard University, Boston, Massachusetts, United States of America

Naishin Fu

Affiliation Division of General Medicine Massachusetts General Hospital, Boston, Massachusetts, United States of America

Elena Losina

Affiliations Division of General Medicine Massachusetts General Hospital, Boston, Massachusetts, United States of America, Departments of Biostatistics and Epidemiology, Boston University School of Public Health, Boston, Massachusetts, United States of America, Harvard University Center for AIDS Research, Harvard University, Boston, Massachusetts, United States of America

Kenneth A. Freedberg

Affiliations Division of General Medicine Massachusetts General Hospital, Boston, Massachusetts, United States of America, Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Departments of Biostatistics and Epidemiology, Boston University School of Public Health, Boston, Massachusetts, United States of America, Harvard University Center for AIDS Research, Harvard University, Boston, Massachusetts, United States of America

Robin Wood

Affiliation Department of Medicine, Desmond Tutu HIV Center, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa

Competing Interests

The authors have read the journal's policy and have the following competing interest: DRK is a consultant to and has received honoraria or research support from Abbott, Boehringer Ingelheim, Gilead, GlaxoSmithKline, Merck and ViiV. This does not alter the authors' adherence to all the PloS ONE policies on sharing data and materials. All other authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JHL CO SG DRK KAF RW. Performed the experiments: JHL SG. Analyzed the data: JHL CO SG DRK EL KAF RW. Contributed reagents/materials/analysis tools: CO RW SG DRK . Wrote the paper: JHL. Critical editing of the Manuscript: JHL CO SG DRK EL KAF RW NF.