About the Authors

Kresten Lindorff-Larsen

Contributed equally to this work with: Kresten Lindorff-Larsen, Paul Maragakis, Stefano Piana

Affiliation D. E. Shaw Research, New York, New York, United States of America

Paul Maragakis

Contributed equally to this work with: Kresten Lindorff-Larsen, Paul Maragakis, Stefano Piana

Affiliation D. E. Shaw Research, New York, New York, United States of America

Stefano Piana

Contributed equally to this work with: Kresten Lindorff-Larsen, Paul Maragakis, Stefano Piana

Affiliation D. E. Shaw Research, New York, New York, United States of America

Michael P. Eastwood

Affiliation D. E. Shaw Research, New York, New York, United States of America

Ron O. Dror

Affiliation D. E. Shaw Research, New York, New York, United States of America

David E. Shaw

David.Shaw@DEShawResearch.com

Affiliations D. E. Shaw Research, New York, New York, United States of America, Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflicts: All the authors are affiliated with D. E. Shaw Research, the funder of this study. This research was conducted within D. E. Shaw Research, of which D.E.S. is the sole beneficial owner and Chief Scientist. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: KL-L PM SP MPE ROD DES. Performed the experiments: KL-L PM SP. Analyzed the data: KL-L PM SP. Contributed reagents/materials/analysis tools: KL-L PM SP. Wrote the paper: KL-L PM SP ROD DES.