About the Authors

Henrik Zetterberg

henrik.zetterberg@clinchem.gu.se

Affiliation Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden

Erik Mörtberg

Affiliation Department of Surgical Sciences, Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden

Linan Song

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

Lei Chang

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

Gail K. Provuncher

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

Purvish P. Patel

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

Evan Ferrell

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

David R. Fournier

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

Cheuk W. Kan

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

Todd G. Campbell

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

Ray Meyer

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

Andrew J. Rivnak

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

Brian A. Pink

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

Kaitlin A. Minnehan

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

Tomasz Piech

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

David M. Rissin

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

David C. Duffy

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

Sten Rubertsson

Affiliation Department of Surgical Sciences, Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden

David H. Wilson

Affiliation Quanterix Corporation, Cambridge, Massachusetts, United States of America

Kaj Blennow

Affiliation Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden

Competing Interests

The authors have read the journal's policy and have the following conflicts: Drs. Song, Chang, Provuncher, Patel, Ferrell, Fournier, Kan, Campbell, Meyer, Rivnak, Pink, Minnehan, Piech, Rissin, Duffy and Wilson are employees at Quanterix Corporation. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. There are no relevant patents and products in relation to this. The other authors have no competing interests.

Author Contributions

Conceived and designed the experiments: HZ KB EM SR DW. Analyzed the data: HZ DW KB. Contributed reagents/materials/analysis tools: LS LC DW. Wrote the paper: HZ DW KB. Performed the ELISA measurements: LS GP PP EF. Performed the SiMoA measurements: DF CK TC RM AR BP KM DR DD. Performed the image analysis: TP. Collected samples: EM SR.