A New Powerful Method for Site-Specific Transgene Stabilization Based on Chromosomal Double-Strand Break Repair

Artem Tkachuk; Maria Kim; Oksana Kravchuk; Mikhail Savitsky

doi:10.1371/journal.pone.0026422

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Open Access

Peer-reviewed

Research Article

A New Powerful Method for Site-Specific Transgene Stabilization Based on Chromosomal Double-Strand Break Repair

Artem Tkachuk ,

Contributed equally to this work with: Artem Tkachuk, Maria Kim

Affiliation Group of Telomere Biology, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia
⨯
Maria Kim ,

Contributed equally to this work with: Artem Tkachuk, Maria Kim

Affiliation Group of Telomere Biology, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia
⨯
Oksana Kravchuk,

Affiliation Group of Telomere Biology, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia
⨯
Mikhail Savitsky

* E-mail: msavitsky@gmail.com

Affiliations Group of Telomere Biology, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia, Center for Medical Studies of Oslo University, Moscow, Russia
⨯

A New Powerful Method for Site-Specific Transgene Stabilization Based on Chromosomal Double-Strand Break Repair

Artem Tkachuk,
Maria Kim,
Oksana Kravchuk,
Mikhail Savitsky

Published: October 17, 2011
https://doi.org/10.1371/journal.pone.0026422

About the Authors

Artem Tkachuk

Contributed equally to this work with: Artem Tkachuk, Maria Kim

Affiliation Group of Telomere Biology, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia

Maria Kim

Contributed equally to this work with: Artem Tkachuk, Maria Kim

Affiliation Group of Telomere Biology, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia

Oksana Kravchuk

Affiliation Group of Telomere Biology, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia

Mikhail Savitsky

* E-mail: msavitsky@gmail.com

Affiliations Group of Telomere Biology, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia, Center for Medical Studies of Oslo University, Moscow, Russia

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MS. Performed the experiments: AT MK OK MS. Analyzed the data: MS AT MK. Wrote the paper: MS AT MK.

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Invertebrate genomics
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Polymerase chain reaction
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DNA repair
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Insect vectors
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Transposable elements
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Drosophila melanogaster
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Cloning
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Transgenic engineering
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