About the Authors

Angela N. Barrett

Affiliations NE Thames Regional Molecular Genetics Laboratories, Great Ormond Street Hospital for Children, London, United Kingdom, University College London Institute of Child Health, London, United Kingdom

Bernhard G. Zimmermann

Affiliation Fluidigm Corporation, South San Francisco, California, United States of America

Darrell Wang

Affiliation University College London Institute of Child Health, London, United Kingdom

Andrew Holloway

Affiliation University College Hospital NHS Foundation Trust, London, United Kingdom

Lyn S. Chitty

l.chitty@ich.ucl.ac.uk

Affiliations University College London Institute of Child Health, London, United Kingdom, University College Hospital NHS Foundation Trust, London, United Kingdom

Competing Interests

The authors have read the journal's policy and have the following conflicts: BZ has shares in the Fluidigm Corporation and is a former employee of the company. The remaining authors have nothing to disclose. This conflict does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: ANB BGZ LSC. Performed the experiments: ANB BGZ DW. Contributed reagents/materials/analysis tools: DW AH. Wrote the paper: ANB BGZ LSC. Analyzed and interpreted the data: ANB BGZ LSC. Collected samples and performed sample preparation: DW AH.