About the Authors

Andrew F. Gardner

gardner@neb.com

Affiliation New England Biolabs, Inc., Ipswich, Massachusetts, United States of America

Chudi Guan

Affiliation New England Biolabs, Inc., Ipswich, Massachusetts, United States of America

William E. Jack

Affiliation New England Biolabs, Inc., Ipswich, Massachusetts, United States of America

Competing Interests

The authors are employed by New England Biolabs, Inc. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. This study was conducted in the Research Department and is not currently intended for product development.

Author Contributions

Conceived and designed the experiments: AFG CG WEJ. Performed the experiments: AFG. Analyzed the data: AFG CG WEJ. Contributed reagents/materials/analysis tools: AFG CG. Wrote the paper: AFG CG WEJ.