About the Authors

Glenn A. Doyle

gadoyle@mail.med.upenn.edu

Affiliation Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Min-Jung Wang

Affiliation Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Andrew D. Chou

Affiliation Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

John U. Oleynick

Affiliation Johnson and Johnson, Malvern, Pennsylvania, United States of America

Steven E. Arnold

Affiliation Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Russell J. Buono

Affiliation Research Service, Department of Veterans Affairs Medical Center, Coatesville, Pennsylvania, United States of America

Thomas N. Ferraro

Affiliation Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Wade H. Berrettini

Affiliation Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Competing Interests

This work does not represent the official views of the United States Government. A subsidiary of the employer of JUO manufactures nicotine replacement therapies for smoking cessation. Neither Johnson & Johnson nor its subsidiaries had any role in the funding of or execution of the studies presented in this paper. JUO's role in these studies was strictly as a statistician. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. All other authors have no disclosures or conflicts of interest to report.

Author Contributions

Conceived and designed the experiments: GAD WHB. Performed the experiments: GAD M-JW ADC. Analyzed the data: GAD TNF JUO. Contributed reagents/materials/analysis tools: RJB SEA. Wrote the paper: GAD.