About the Authors

Mark M. Yore

Affiliation Department of Pharmacology, Dartmouth Medical School, Hanover, New Hampshire, United States of America

Arminja N. Kettenbach

Affiliations Department of Genetics, Dartmouth Medical School, Hanover, New Hampshire, United States of America, Norris Cotton Cancer Center, Lebanon, New Hampshire, United States of America

Michael B. Sporn

Contributed equally to this work with: Michael B. Sporn, Scott A. Gerber, Karen T. Liby

Michael.Sporn@dartmouth.edu

Affiliation Department of Pharmacology, Dartmouth Medical School, Hanover, New Hampshire, United States of America

Scott A. Gerber

Contributed equally to this work with: Michael B. Sporn, Scott A. Gerber, Karen T. Liby

Affiliations Department of Genetics, Dartmouth Medical School, Hanover, New Hampshire, United States of America, Norris Cotton Cancer Center, Lebanon, New Hampshire, United States of America

Karen T. Liby

Contributed equally to this work with: Michael B. Sporn, Scott A. Gerber, Karen T. Liby

Affiliation Department of Pharmacology, Dartmouth Medical School, Hanover, New Hampshire, United States of America

Competing Interests

Karen Liby and Michael Sporn are inventors on patents dealing with chemical synthesis of new triterpenoids and their application in treatment of cancer, as well as in inflammatory diseases, including human kidney disease (patent 6,974,801 issued 1/1/2004). They strongly adhere to the PLoS ONE policy on sharing of data and materials. The Sporn Laboratory has a long history of being extremely free in sharing of materials, with no strings attached, with other laboratories throughout the world.

Author Contributions

Conceived and designed the experiments: MMY. Performed the experiments: MMY ANK. Analyzed the data: MMY ANK KTL SAG MBS. Contributed reagents/materials/analysis tools: ANK SAG. Wrote the paper: MMY ANK KTL SAG MBS.