Structural and Functional Evaluation of C. elegans Filamins FLN-1 and FLN-2

Christina R. DeMaso; Ismar Kovacevic; Alper Uzun; Erin J. Cram

doi:10.1371/journal.pone.0022428

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Open Access

Peer-reviewed

Research Article

Structural and Functional Evaluation of C. elegans Filamins FLN-1 and FLN-2

Christina R. DeMaso,

Affiliation Department of Biology, Center for Interdisciplinary Research on Complex Systems, Northeastern University, Boston, Massachusetts, United States of America
⨯
Ismar Kovacevic,

Affiliation Department of Biology, Center for Interdisciplinary Research on Complex Systems, Northeastern University, Boston, Massachusetts, United States of America
⨯
Alper Uzun,

Affiliation Department of Pediatrics, Women and Infants Hospital of Rhode Island, Brown Alpert Medical School, Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America
⨯
Erin J. Cram

* E-mail: e.cram@neu.edu

Affiliation Department of Biology, Center for Interdisciplinary Research on Complex Systems, Northeastern University, Boston, Massachusetts, United States of America
⨯

Structural and Functional Evaluation of C. elegans Filamins FLN-1 and FLN-2

Christina R. DeMaso,
Ismar Kovacevic,
Alper Uzun,
Erin J. Cram

Published: July 25, 2011
https://doi.org/10.1371/journal.pone.0022428

About the Authors

Christina R. DeMaso

Affiliation Department of Biology, Center for Interdisciplinary Research on Complex Systems, Northeastern University, Boston, Massachusetts, United States of America

Ismar Kovacevic

Affiliation Department of Biology, Center for Interdisciplinary Research on Complex Systems, Northeastern University, Boston, Massachusetts, United States of America

Alper Uzun

Affiliation Department of Pediatrics, Women and Infants Hospital of Rhode Island, Brown Alpert Medical School, Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America

Erin J. Cram

* E-mail: e.cram@neu.edu

Affiliation Department of Biology, Center for Interdisciplinary Research on Complex Systems, Northeastern University, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EJC CRD IK. Performed the experiments: CRD IK. Analyzed the data: CRD IK. Contributed reagents/materials/analysis tools: AU. Wrote the paper: CRD IK EJC.

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Caenorhabditis elegans
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Actins
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Sequence alignment
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Dimerization
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Integrins
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Protein domains
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Drosophila melanogaster
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Invertebrate genomics
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