About the Authors
- Fuqu Yu
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Contributed equally to this work with: Fuqu Yu, Ibrahim Al-Shyoukh
Current address: Johnson & Johnson Pharmaceutical Research & Development LLC, San Diego, California, United States of America,
Affiliation Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America
- Ibrahim Al-Shyoukh
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Contributed equally to this work with: Fuqu Yu, Ibrahim Al-Shyoukh
Affiliations Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America, Mechanical and Aerospace Engineering Department, University of California Los Angeles, Los Angeles, California, United States of America
- Jiaying Feng
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Affiliation Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America
- Xudong Li
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Affiliation Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America
- Chia Wei Liao
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Affiliation Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America
- Chih-Ming Ho
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Affiliation Mechanical and Aerospace Engineering Department, University of California Los Angeles, Los Angeles, California, United States of America
- Jeff S. Shamma
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Affiliation School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, Georgia, United States of America
- Ren Sun
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* E-mail: rsun@mednet.ucla.edu
Affiliation Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: FY IAS CMH JSS RS. Performed the experiments: FY JF XL CWL. Analyzed the data: IAS FY RS. Contributed reagents/materials/analysis tools: FY IAS JF XL RS. Wrote the paper: IAS FY RS. Introduced the idea to optimize drug combinations using a mathematical feedback algorithm: CHM.