About the Authors

Anthony Cammarato

Affiliations Development and Aging Program, NASCR Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America, Department of Biology and the Heart Institute, San Diego State University, San Diego, California, United States of America

Christian H. Ahrens

Affiliation Quantitative Model Organism Proteomics, Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland

Nakissa N. Alayari

Affiliations Development and Aging Program, NASCR Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America, Department of Biology and the Heart Institute, San Diego State University, San Diego, California, United States of America

Ermir Qeli

Affiliation Quantitative Model Organism Proteomics, Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland

Jasma Rucker

Affiliation Division of Cardiology, Institute of Molecular Cardiobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Mary C. Reedy

Affiliation Department of Cell Biology, Duke University School of Medicine, Durham, North Carolina, United States of America

Christian M. Zmasek

Affiliation Bioinformatics and Systems Biology Program, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

Marjan Gucek

Affiliation Johns Hopkins Proteomics Core, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Robert N. Cole

Affiliation Johns Hopkins Proteomics Core, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Jennifer E. Van Eyk

Affiliation Division of Cardiology, Departments of Biological Chemistry and Biomedical Engineering, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, United States of America

Rolf Bodmer

Affiliation Development and Aging Program, NASCR Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

Brian O'Rourke

Affiliation Division of Cardiology, Institute of Molecular Cardiobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Sanford I. Bernstein

Affiliation Department of Biology and the Heart Institute, San Diego State University, San Diego, California, United States of America

D. Brian Foster

dbrianfoster@jhmi.edu

Affiliation Division of Cardiology, Institute of Molecular Cardiobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AC DBF. Performed the experiments: AC NNA JR MCR MG DBF. Analyzed the data: AC CHA EQ CMZ DBF. Contributed reagents/materials/analysis tools: CHA EQ RNC JVE RB BOR SIB. Wrote the paper: AC CHA DBF. Edited the paper: EQ CMZ MG RNC JVE RB BOR SIB.