About the Authors

Emeli Lundström

emeli.lundstrom@ki.se

Affiliation Department of Rheumatology, Karolinska Institutet, Stockholm, Sweden

Toinette Hartshorne

Affiliation Applied Biosystems, Foster City, California, United States of America

Kelly Li

Affiliation Applied Biosystems, Foster City, California, United States of America

Staffan Lindblad

Affiliation Department of Rheumatology, Karolinska Institutet, Stockholm, Sweden

Marius C. Wick

Affiliations Department of Rheumatology, Karolinska Institutet, Stockholm, Sweden, Department of Radiology, Innsbruck Medical University, Innsbruck, Austria

Camilla Bengtsson

Affiliation Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

Lars Alfredsson

Affiliation Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

Lars Klareskog

Affiliation Department of Rheumatology, Karolinska Institutet, Stockholm, Sweden

Leonid Padyukov

Affiliation Department of Rheumatology, Karolinska Institutet, Stockholm, Sweden

Competing Interests

Applied Biosystems (AB) provided reagents for genotyping of GSTM1 for this study. Toinette Hartshorne and Kelly Li are employed by AB. Neither AB nor any of its employees had a role in study design, data collection and analysis, decision to publish. Toinette Hartshorne and Kelly Li were involved in preparation of the manuscripts and are co-authors for this paper. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: EL LK LP. Performed the experiments: EL CB MCW SL. Analyzed the data: EL CB LA LK LP. Contributed reagents/materials/analysis tools: EL CB LA LK SL MCW KL TH LP. Wrote the paper: EL CB MCW TH KL LA LK LP.