About the Authors

Paul A. Adlard

p.adlard@mhri.edu.au

Affiliations Oxidation Biology Laboratory, The Mental Health Research Institute, Parkville, Victoria, Australia, Synaptic Neurobiology Laboratory, The Mental Health Research Institute, Parkville, Victoria, Australia, Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia

Laura Bica

Affiliations Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia, Centre for Neuroscience, The University of Melbourne, Parkville, Victoria, Australia

Anthony R. White

Affiliations Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia, Centre for Neuroscience, The University of Melbourne, Parkville, Victoria, Australia

Milawaty Nurjono

Affiliation Oxidation Biology Laboratory, The Mental Health Research Institute, Parkville, Victoria, Australia

Gulay Filiz

Affiliation Oxidation Biology Laboratory, The Mental Health Research Institute, Parkville, Victoria, Australia

Peter J. Crouch

Affiliations Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia, Centre for Neuroscience, The University of Melbourne, Parkville, Victoria, Australia

Paul S. Donnelly

Affiliations Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia, School of Chemistry, The University of Melbourne, Parkville, Victoria, Australia

Roberto Cappai

Affiliations Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia

David I. Finkelstein

Contributed equally to this work with: David I. Finkelstein, Ashley I. Bush

Affiliations Oxidation Biology Laboratory, The Mental Health Research Institute, Parkville, Victoria, Australia, Synaptic Neurobiology Laboratory, The Mental Health Research Institute, Parkville, Victoria, Australia, Centre for Neuroscience, The University of Melbourne, Parkville, Victoria, Australia

Ashley I. Bush

Contributed equally to this work with: David I. Finkelstein, Ashley I. Bush

Affiliations Oxidation Biology Laboratory, The Mental Health Research Institute, Parkville, Victoria, Australia, Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia

Competing Interests

PAA, DIF and AIB are consultants to Prana Biotechnology Ltd. PAA, DIF, AIB, RC are minor shareholders in Prana Biotechnology Ltd. ARW, LB, PSD, PJC, MN, GF report no financial disclosures or conflicts of interest. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: PAA ARW RC DIF. Performed the experiments: LB MN GF. Analyzed the data: PAA LB ARW MN GF DIF. Contributed reagents/materials/analysis tools: PJC PSD. Wrote the paper: PAA AIB.