About the Authors

Tara L. Lin

tlin@lsuhsc.edu (TLL); matsuwi@jhmi.edu (WM)

Affiliation Section of Hematology and Oncology, Department of Internal Medicine, LSU Health Sciences Center, New Orleans, Louisiana, United States of America

Qiuju H. Wang

Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Patrick Brown

Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Craig Peacock

Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Akil A. Merchant

Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Sarah Brennan

Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Evan Jones

Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Karen McGovern

Affiliation Infinity Pharmaceuticals, Cambridge, Massachusetts, United States of America

D. Neil Watkins

Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Kathleen M. Sakamoto

Affiliation Gwynne Hazen Cherry Memorial Laboratories, Department of Pediatrics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America

William Matsui

tlin@lsuhsc.edu (TLL); matsuwi@jhmi.edu (WM)

Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Competing Interests

Karen McGovern is an employee of Infinity Pharmaceuticals. William Matsui has served as a consultant to Infinity Pharmaceuticals. Kathleen M. Sakamoto has received research support from Abbott Laboratories and Genentech, Inc. The remaining authors have declared that no competing interests exist. The authors confirm that this does not alter adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: TLL WM CP AAM DNW. Performed the experiments: TLL QHW SB EJ. Analyzed the data: TLL KMS WM. Contributed reagents/materials/analysis tools: PB KM. Wrote the paper: TLL KMS WM.