About the Authors

Sebastian Jaenicke

Affiliation Computational Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany

Christina Ander

Affiliation Computational Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany

Thomas Bekel

Affiliation Computational Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany

Regina Bisdorf

Affiliation Computational Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany

Marcus Dröge

Affiliation Roche Diagnostics GmbH, Penzberg, Germany

Karl-Heinz Gartemann

Affiliation Department of Genetechnology/Microbiology, Bielefeld University, Bielefeld, Germany

Sebastian Jünemann

Affiliations Computational Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany, Department of Periodontology, University Hospital Münster, Münster, Germany

Olaf Kaiser

Affiliation Roche Diagnostics GmbH, Penzberg, Germany

Lutz Krause

Affiliation Division of Genetics and Population Health, Queensland Institute of Medical Research, Herston, Australia

Felix Tille

Affiliation Computational Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany

Martha Zakrzewski

Affiliation Computational Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany

Alfred Pühler

Affiliation Institute for Genome Research and Systems Biology, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany

Andreas Schlüter

Contributed equally to this work with: Andreas Schlüter, Alexander Goesmann

Affiliation Institute for Genome Research and Systems Biology, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany

Alexander Goesmann

Contributed equally to this work with: Andreas Schlüter, Alexander Goesmann

agoesman@CeBiTec.Uni-Bielefeld.DE

Affiliation Computational Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany

Competing Interests

Marcus Dröge and Olaf Kaiser are employees of Roche Diagnostics GmbH, Germany. This does not affect the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: S. Jaenicke AP AS AG. Performed the experiments: S. Jaenicke MD OK. Analyzed the data: S. Jaenicke CA TB RB KHG S. Jünemann LK FT MZ AS AG. Contributed reagents/materials/analysis tools: S. Jaenicke MD OK. Wrote the paper: S. Jaenicke S. Jünemann LK AS.