About the Authors

Anne Braun

Contributed equally to this work with: Anne Braun, Lilibeth Dofiles

bostonegles@yahoo.com

Affiliation Charles River Laboratories, Preclinical Services Massachusetts, Shrewsbury, Massachusetts, United States of America

Lilibeth Dofiles

Contributed equally to this work with: Anne Braun, Lilibeth Dofiles

Affiliation Elan Pharmaceuticals, Inc., South San Francisco, California, United States of America

Serge Rousselle

Affiliation Alizee Pathology, LLC, Thurmont, Maryland, United States of America

Luis Guerrero

Affiliation Charles River Laboratories, Preclinical Services Massachusetts, Shrewsbury, Massachusetts, United States of America

Jane Gunther

Affiliation Elan Pharmaceuticals, Inc., South San Francisco, California, United States of America

Ted Yednock

Affiliation Elan Pharmaceuticals, Inc., South San Francisco, California, United States of America

Alain Stricker-Krongrad

Affiliation Charles River Laboratories, Preclinical Services Massachusetts, Shrewsbury, Massachusetts, United States of America

Elizabeth Messersmith

Affiliation Elan Pharmaceuticals, Inc., South San Francisco, California, United States of America

Competing Interests

Lilibeth Dofiles, Jane Gunther, Ted Yednock and Elizabeth Messersmith are employees of Elan Pharmaceuticals, the funder of this work. While these authors are employed by Elan Pharmaceuticals, it does not alter their adherance to all of the PLoS ONE policies on sharing data and materials. While Serge Rousselle is an employee of Alizee Pharmacology LLC, it does not alter his adherance to all of the PLoS ONE policies on sharing data and materials. While Anne Braun, Luis Guerrero and Alain Stricker-Krongrad are employees of Charles River Laboratories, it does not alter their adherance to all of the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AB LD SR JG TY ASK EM. Performed the experiments: AB SR LG. Analyzed the data: AB LD SR. Contributed reagents/materials/analysis tools: LD LG JG. Wrote the paper: AB LD ASK.