Characterization of Engineered Actin Binding Proteins That Control Filament Assembly and Structure

Crista M. Brawley; Serdar Uysal; Anthony A. Kossiakoff; Ronald S. Rock

doi:10.1371/journal.pone.0013960

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Open Access

Peer-reviewed

Research Article

Characterization of Engineered Actin Binding Proteins That Control Filament Assembly and Structure

Crista M. Brawley ,

Contributed equally to this work with: Crista M. Brawley, Serdar Uysal

Affiliation Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois, United States of America
⨯
Serdar Uysal ,

Contributed equally to this work with: Crista M. Brawley, Serdar Uysal

Affiliation Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois, United States of America
⨯
Anthony A. Kossiakoff ,

* E-mail: koss@bsd.uchicago.edu (AAK); rrock@uchicago.edu (RSR)

Affiliation Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois, United States of America
⨯
Ronald S. Rock

* E-mail: koss@bsd.uchicago.edu (AAK); rrock@uchicago.edu (RSR)

Affiliation Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois, United States of America
⨯

Characterization of Engineered Actin Binding Proteins That Control Filament Assembly and Structure

Crista M. Brawley,
Serdar Uysal,
Anthony A. Kossiakoff,
Ronald S. Rock

Published: November 12, 2010
https://doi.org/10.1371/journal.pone.0013960

About the Authors

Crista M. Brawley

Contributed equally to this work with: Crista M. Brawley, Serdar Uysal

Affiliation Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois, United States of America

Serdar Uysal

Contributed equally to this work with: Crista M. Brawley, Serdar Uysal

Affiliation Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois, United States of America

Anthony A. Kossiakoff

* E-mail: koss@bsd.uchicago.edu (AAK); rrock@uchicago.edu (RSR)

Affiliation Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois, United States of America

Ronald S. Rock

* E-mail: koss@bsd.uchicago.edu (AAK); rrock@uchicago.edu (RSR)

Affiliation Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CMB SU AK RSR. Performed the experiments: CMB SU. Analyzed the data: CMB. Contributed reagents/materials/analysis tools: SU AK RSR. Wrote the paper: CMB AK RSR.

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Actins
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Actin filaments
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Polymerization
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Actin polymerization
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Phage display
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Depolymerization
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Deoxyribonucleases
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Nucleation
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