About the Authors

Stephen F. Hughes

stephen.hughes@chester.ac.uk

Affiliations Department of Biological Sciences, University of Chester, Chester, United Kingdom, Leopold Muller Arthritis Research Centre, The Robert Jones and Agnes Hunt Orthopaedic Hospital, Medical School, Keele University, Staffordshire, United Kingdom

Beverly D. Hendricks

Affiliation Haematology Department, Glan Clwyd Hospital, Conwy, United Kingdom

David R. Edwards

Affiliation Haematology Department, Gwynedd Hospital, Gwynedd, United Kingdom

Jim F. Middleton

Affiliation Leopold Muller Arthritis Research Centre, The Robert Jones and Agnes Hunt Orthopaedic Hospital, Medical School, Keele University, Staffordshire, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SFH DRE JFM. Performed the experiments: SFH BDH JFM. Analyzed the data: SFH DRE JFM. Contributed reagents/materials/analysis tools: SFH BDH. Wrote the paper: SFH JFM. Provided clinical advice: DRE.