About the Authors

Philipp A. Jaeger

Affiliations Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, United States of America, Institut für Chemie und Biochemie, Freie Universität Berlin, Berlin, Germany

Fiona Pickford

Current address: Merck Research Laboratories, Boston, Massachusetts, United States of America

Affiliation Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, United States of America

Chung-Huan Sun

Affiliation Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, United States of America

Kurt M. Lucin

Affiliation Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, United States of America

Eliezer Masliah

Affiliation Department of Neurosciences and Pathology, University of California San Diego, La Jolla, California, United States of America

Tony Wyss-Coray

twc@stanford.edu

Affiliations Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, United States of America, Geriatric Research Education and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, California, United States of America

Competing Interests

The authors received partial funding from Biogen Idec. However, no competing interests exist, and all data and materials are available to the scientific community in adherence to all the PLoS ONE policies.

Author Contributions

Conceived and designed the experiments: PAJ FP TWC. Performed the experiments: PAJ FP CHS KML. Analyzed the data: PAJ FP KML. Contributed reagents/materials/analysis tools: EM. Wrote the paper: PAJ TWC.