About the Authors

Michiro Susa

Contributed equally to this work with: Michiro Susa, Arun K. Iyer

Affiliations Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Arun K. Iyer

Contributed equally to this work with: Michiro Susa, Arun K. Iyer

Current address: Department of Radiology & Biomedical Imaging, Center for Molecular & Functional Imaging, University of California San Francisco, San Francisco, California, United States of America

Affiliation Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, Massachusetts, United States of America

Keinosuke Ryu

Affiliations Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Edwin Choy

Affiliation Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Francis J. Hornicek

Affiliations Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Henry Mankin

Affiliation Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Lara Milane

Affiliation Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, Massachusetts, United States of America

Mansoor M. Amiji

Affiliation Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, Massachusetts, United States of America

Zhenfeng Duan

zduan@partners.org

Affiliations Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MS AKI FJH HM MMA ZD. Performed the experiments: MS AKI KR. Analyzed the data: AKI EC LM. Contributed reagents/materials/analysis tools: AKI FJH MMA ZD. Wrote the paper: MS.