About the Authors

Ning Li

Contributed equally to this work with: Ning Li, Scott Thompson

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Scott Thompson

Contributed equally to this work with: Ning Li, Scott Thompson

Affiliation The Wistar Institute, Philadelphia, Pennsylvania, United States of America

David C. Schultz

Affiliation The Wistar Institute, Philadelphia, Pennsylvania, United States of America

Weiliang Zhu

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Hualiang Jiang

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Cheng Luo

lieberman@wistar.org (PML); cluo@mail.shcnc.ac.cn (CL)

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Paul M. Lieberman

lieberman@wistar.org (PML); cluo@mail.shcnc.ac.cn (CL)

Affiliation The Wistar Institute, Philadelphia, Pennsylvania, United States of America

Competing Interests

Paul Lieberman has a competing interest as an officer (Founder/Owner and President) in a small biotechnology company called Vironika. A provisional patent has been submitted based on this work. No funding from Vironika was used for this study. The authors confirm that this does not alter their adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: ST CL PML. Performed the experiments: NL ST DCS WZ HJ CL. Analyzed the data: NL ST DCS WZ HJ CL PML. Contributed reagents/materials/analysis tools: DCS HJ CL. Wrote the paper: CL PML.