About the Authors

Andrea Kuenzli

Affiliation Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland

Heiner C. Bucher

Affiliation Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland

Inder Anand

Affiliation Cardiovascular Division, University of Minnesota Medical School, Veterans Affairs Medical Center, Minneapolis, Minnesota, United States of America

Gregory Arutiunov

Affiliation Russian State Medical University, Moscow, Russian Federation

Leo C. Kum

Affiliation Division of Cardiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region, People's Republic of China

Robert McKelvie

Affiliation Population Health Research Institute, Hamilton Health Sciences - General Site and McMaster University, Hamilton, Ontario, Canada

Rizwan Afzal

Affiliation Population Health Research Institute, Hamilton Health Sciences - General Site and McMaster University, Hamilton, Ontario, Canada

Michel White

Affiliations Research Center, Montreal Heart Institute, Montréal, Quebec, Canada, Université de Montréal, Montréal, Quebec, Canada

Alain J. Nordmann

nordmanna@uhbs.ch

Affiliation Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland

Competing Interests

AstraZeneca supported the research with an unrestricted grant, but the funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. None of the authors are employed by AstraZeneca. The authors did not receive consultant's fees from AstraZeneca. They do not have patents or products in development related to the content of this paper. The unrestricted grant from AstraZeneca does not alter their adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in our guide for authors http://www.plosone.org/static/policies.action#sharing.

Author Contributions

Conceived and designed the experiments: HCB IA GA LCK RM RA MW AJN. Analyzed the data: AK IA GA LCK RM RA MW AJN. Wrote the paper: AK HCB AJN.