Expression of Pseudomonas aeruginosa CupD Fimbrial Genes Is Antagonistically Controlled by RcsB and the EAL-Containing PvrR Response Regulators

Helga Mikkelsen; Geneviève Ball; Caroline Giraud; Alain Filloux

doi:10.1371/journal.pone.0006018

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Peer-reviewed

Research Article

Expression of Pseudomonas aeruginosa CupD Fimbrial Genes Is Antagonistically Controlled by RcsB and the EAL-Containing PvrR Response Regulators

Helga Mikkelsen,

Affiliation Imperial College London, Division of Cell and Molecular Biology, Centre for Molecular Microbiology and Infection, South Kensington Campus, London, United Kingdom
⨯
Geneviève Ball,

Affiliation Laboratoire d'Ingénierie des Systèmes Macromoléculaires, UPR9027, CNRS-IBSM, Marseille, France
⨯
Caroline Giraud,

Affiliation Laboratoire d'Ingénierie des Systèmes Macromoléculaires, UPR9027, CNRS-IBSM, Marseille, France
⨯
Alain Filloux

* E-mail: a.filloux@imperial.ac.uk

Affiliations Imperial College London, Division of Cell and Molecular Biology, Centre for Molecular Microbiology and Infection, South Kensington Campus, London, United Kingdom, Laboratoire d'Ingénierie des Systèmes Macromoléculaires, UPR9027, CNRS-IBSM, Marseille, France
⨯

Expression of Pseudomonas aeruginosa CupD Fimbrial Genes Is Antagonistically Controlled by RcsB and the EAL-Containing PvrR Response Regulators

Helga Mikkelsen,
Geneviève Ball,
Caroline Giraud,
Alain Filloux

Published: June 23, 2009
https://doi.org/10.1371/journal.pone.0006018

About the Authors

Helga Mikkelsen

Affiliation Imperial College London, Division of Cell and Molecular Biology, Centre for Molecular Microbiology and Infection, South Kensington Campus, London, United Kingdom

Geneviève Ball

Affiliation Laboratoire d'Ingénierie des Systèmes Macromoléculaires, UPR9027, CNRS-IBSM, Marseille, France

Caroline Giraud

Affiliation Laboratoire d'Ingénierie des Systèmes Macromoléculaires, UPR9027, CNRS-IBSM, Marseille, France

Alain Filloux

* E-mail: a.filloux@imperial.ac.uk

Affiliations Imperial College London, Division of Cell and Molecular Biology, Centre for Molecular Microbiology and Infection, South Kensington Campus, London, United Kingdom, Laboratoire d'Ingénierie des Systèmes Macromoléculaires, UPR9027, CNRS-IBSM, Marseille, France

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HM AF. Performed the experiments: HM GB CG. Analyzed the data: HM GB CG AF. Wrote the paper: HM AF.

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Bacterial biofilms
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Gene expression
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Pseudomonas aeruginosa
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Pili and fimbriae
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Regulator genes
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Gene regulation
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Phenotypes
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Pathogen motility
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