About the Authors

Sarah H. Louie

Current address: Department of Biochemistry, University of Virginia, Charlottesville, Virginia, United States of America

Affiliation Howard Hughes Medical Institute, Department of Pharmacology, and Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America

Xiao Yong Yang

Affiliation Department of Psychiatry, and Graduate Program in Developmental Biology, Program in Biological Sciences, University of California San Francisco, San Francisco, California, United States of America

William H. Conrad

Affiliation Howard Hughes Medical Institute, Department of Pharmacology, and Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America

Jeanot Muster

Affiliation Howard Hughes Medical Institute, Department of Pharmacology, and Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America

Stephane Angers

Current address: Faculty of Pharmacy, and Department of Biochemistry, University of Toronto, Toronto, Canada

Affiliation Howard Hughes Medical Institute, Department of Pharmacology, and Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America

Randall T. Moon

Affiliation Howard Hughes Medical Institute, Department of Pharmacology, and Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America

Benjamin N. R. Cheyette

benjamin.cheyette@ucsf.edu

Affiliation Department of Psychiatry, and Graduate Program in Developmental Biology, Program in Biological Sciences, University of California San Francisco, San Francisco, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SHL XYY WHC JM SA RM BNRC. Performed the experiments: SHL XYY WHC JM SA BNRC. Analyzed the data: SHL XYY WHC SA RM BNRC. Contributed reagents/materials/analysis tools: SHL SA RM BNRC. Wrote the paper: SHL RM BNRC.