About the Authors

Ian C. Grieve

Affiliation MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital, London, United Kingdom

Nicholas J. Dickens

Affiliations MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital, London, United Kingdom, Institute of Cancer Research, Belmont, Sutton, Surrey, United Kingdom

Michal Pravenec

Affiliations Institute of Biology and Medical Genetics, First Faculty of Medicine and General Teaching Hospital, Charles University, Prague, Czech Republic, Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic

Vladimir Kren

Affiliations Institute of Biology and Medical Genetics, First Faculty of Medicine and General Teaching Hospital, Charles University, Prague, Czech Republic, Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic

Norbert Hubner

Affiliation Max-Delbrűck-Center for Molecular Medicine, Berlin-Buch, Berlin, Germany

Stuart A. Cook

Affiliations MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital, London, United Kingdom, National Heart and Lung Institute, Imperial College, London, United Kingdom

Timothy J. Aitman

Affiliation MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital, London, United Kingdom

Enrico Petretto

enrico.petretto@imperial.ac.uk

Affiliations MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital, London, United Kingdom, Division of Epidemiology, Public Health and Primary Care, Imperial College, London, United Kingdom

Jonathan Mangion

Affiliation MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ICG JM. Performed the experiments: ICG. Analyzed the data: ICG NJD EP JM. Contributed reagents/materials/analysis tools: MP VK NH SC TJA. Wrote the paper: ICG. Assisted in the development of statistical and computational methods: EP NJD JM. Assisted in revision of the manuscript: EP TJA. Supervised the writing of the paper: EP. Advised on study design and implementation: TJA. Supervised the analysis: JM.