Commercial Nucleic-Acid Amplification Tests for Diagnosis of Pulmonary Tuberculosis in Respiratory Specimens: Meta-Analysis and Meta-Regression

Daphne I. Ling; Laura L. Flores; Lee W. Riley; Madhukar Pai

doi:10.1371/journal.pone.0001536

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Open Access

Peer-reviewed

Research Article

Commercial Nucleic-Acid Amplification Tests for Diagnosis of Pulmonary Tuberculosis in Respiratory Specimens: Meta-Analysis and Meta-Regression

Daphne I. Ling,

Affiliation Division of Epidemiology, School of Public Health, University of California, Berkeley, California, United States of America
⨯
Laura L. Flores,

Affiliation Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, San Francisco, California, United States of America
⨯
Lee W. Riley,

Affiliations Division of Epidemiology, School of Public Health, University of California, Berkeley, California, United States of America, Division of Infectious Diseases, School of Public Health, University of California, Berkeley, California, United States of America
⨯
Madhukar Pai

*To whom correspondence should be addressed. E-mail: madhukar.pai@mcgill.ca

Affiliation Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada
⨯

Commercial Nucleic-Acid Amplification Tests for Diagnosis of Pulmonary Tuberculosis in Respiratory Specimens: Meta-Analysis and Meta-Regression

Daphne I. Ling,
Laura L. Flores,
Lee W. Riley,
Madhukar Pai

Published: February 6, 2008
https://doi.org/10.1371/journal.pone.0001536

About the Authors

Daphne I. Ling

Affiliation Division of Epidemiology, School of Public Health, University of California, Berkeley, California, United States of America

Laura L. Flores

Affiliation Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, San Francisco, California, United States of America

Lee W. Riley

Affiliations Division of Epidemiology, School of Public Health, University of California, Berkeley, California, United States of America, Division of Infectious Diseases, School of Public Health, University of California, Berkeley, California, United States of America

Madhukar Pai

*To whom correspondence should be addressed. E-mail: madhukar.pai@mcgill.ca

Affiliation Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Participated in the study design: LR. Assisted in the analysis: LR. Participated in study selection and data extraction: LF DL. Assisted in the data analysis: LF. Performed data analysis: DL. Wrote the draft manuscript: DL. Designed the study: MP DL. Assisted in data analysis and interpretation: MP. Edited the manuscript: MP LF LR. Provided supervision: MP.

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Metaanalysis
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Tuberculosis
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Tuberculosis diagnosis and management
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Mycobacterium tuberculosis
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Sputum
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Diagnostic medicine
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Polymerase chain reaction
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Nucleic acids
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