About the Authors

Chao Cheng

Affiliation Molecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, California, United States of America

Paola Fabrizio

Affiliation Andrus Gerontology Center and Department of Biological Sciences, University of Southern California, Los Angeles, California, United States of America

Huanying Ge

Affiliation Molecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, California, United States of America

Min Wei

Affiliation Andrus Gerontology Center and Department of Biological Sciences, University of Southern California, Los Angeles, California, United States of America

Valter D. Longo

Affiliation Andrus Gerontology Center and Department of Biological Sciences, University of Southern California, Los Angeles, California, United States of America

Lei M. Li

To whom correspondence should be addressed. E-mail: lilei@usc.edu

Affiliations Molecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, California, United States of America, Department of Mathematics, University of Southern California, Los Angeles, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VL LL PF. Performed the experiments: PF MW. Analyzed the data: LL CC HG. Contributed reagents/materials/analysis tools: VL LL CC PF. Wrote the paper: LL CC.