About the Authors

Orest Szczurko

Affiliation Division of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada

Kieran Cooley

Affiliation Division of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada

Jason W. Busse

Affiliation Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada

Dugald Seely

Affiliation Division of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada

Bob Bernhardt

Affiliation Division of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada

Gordon H. Guyatt

Affiliation Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada

Qi Zhou

Affiliation Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada

Edward J. Mills

To whom correspondence should be addressed. E-mail: millsej@mcmaster.ca

Affiliation Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EM JB OS KC DS BB GG. Performed the experiments: OS KC. Analyzed the data: EM JB OS KC DS GG QZ. Contributed reagents/materials/analysis tools: EM OS KC GG QZ. Wrote the paper: EM JB OS KC DS BB GG. Other: Enrolled patients: EM.