Cyclin E and CDK2 Repress the Terminal Differentiation of Quiescent Cells after Asymmetric Division in C. elegans

Masaki Fujita; Hisako Takeshita; Hitoshi Sawa

doi:10.1371/journal.pone.0000407

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Open Access

Peer-reviewed

Research Article

Cyclin E and CDK2 Repress the Terminal Differentiation of Quiescent Cells after Asymmetric Division in C. elegans

Masaki Fujita,

Affiliation Laboratory for Cell Fate Decision, RIKEN, Center for Developmental Biology, Kobe, Japan
⨯
Hisako Takeshita,

Affiliation Laboratory for Cell Fate Decision, RIKEN, Center for Developmental Biology, Kobe, Japan
⨯
Hitoshi Sawa

*To whom correspondence should be addressed. E-mail: sawa@cdb.riken.jp

Affiliations Laboratory for Cell Fate Decision, RIKEN, Center for Developmental Biology, Kobe, Japan, Department of Biology, Graduate School of Science, Kobe University, Kobe, Japan
⨯

Cyclin E and CDK2 Repress the Terminal Differentiation of Quiescent Cells after Asymmetric Division in C. elegans

Masaki Fujita,
Hisako Takeshita,
Hitoshi Sawa

Published: May 2, 2007
https://doi.org/10.1371/journal.pone.0000407

About the Authors

Masaki Fujita

Affiliation Laboratory for Cell Fate Decision, RIKEN, Center for Developmental Biology, Kobe, Japan

Hisako Takeshita

Affiliation Laboratory for Cell Fate Decision, RIKEN, Center for Developmental Biology, Kobe, Japan

Hitoshi Sawa

*To whom correspondence should be addressed. E-mail: sawa@cdb.riken.jp

Affiliations Laboratory for Cell Fate Decision, RIKEN, Center for Developmental Biology, Kobe, Japan, Department of Biology, Graduate School of Science, Kobe University, Kobe, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HS MF. Performed the experiments: MF HT. Analyzed the data: MF. Contributed reagents/materials/analysis tools: HT. Wrote the paper: HS.

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Cell cycle and cell division
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Cell differentiation
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Cyclins
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Gonads
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Caenorhabditis elegans
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Phenotypes
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Cell polarity
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Synthesis phase
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