Restructuring of Pancreatic Islets and Insulin Secretion in a Postnatal Critical Window

Cristina Aguayo-Mazzucato; Carmen Sanchez-Soto; Victoria Godinez-Puig; Gabriel Gutiérrez-Ospina; Marcia Hiriart

doi:10.1371/journal.pone.0000035

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Open Access

Peer-reviewed

Research Article

Restructuring of Pancreatic Islets and Insulin Secretion in a Postnatal Critical Window

Cristina Aguayo-Mazzucato,

Affiliation Department of Biophysics, Institute of Cellular Physiology, National Autonomous University of México, Mexico City, Mexico
⨯
Carmen Sanchez-Soto,

Affiliation Department of Biophysics, Institute of Cellular Physiology, National Autonomous University of México, Mexico City, Mexico
⨯
Victoria Godinez-Puig,

Affiliation Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico
⨯
Gabriel Gutiérrez-Ospina,

Affiliation Department of Cell Biology and Physiology, Biomedical Research Institute, National Autonomous University of México, Mexico City, Mexico
⨯
Marcia Hiriart

*To whom correspondence should be addressed. E-mail: mhiriart@ifc.unam.mx

Affiliation Department of Biophysics, Institute of Cellular Physiology, National Autonomous University of México, Mexico City, Mexico
⨯

Restructuring of Pancreatic Islets and Insulin Secretion in a Postnatal Critical Window

Cristina Aguayo-Mazzucato,
Carmen Sanchez-Soto,
Victoria Godinez-Puig,
Gabriel Gutiérrez-Ospina,
Marcia Hiriart

Published: December 20, 2006
https://doi.org/10.1371/journal.pone.0000035

About the Authors

Cristina Aguayo-Mazzucato

Affiliation Department of Biophysics, Institute of Cellular Physiology, National Autonomous University of México, Mexico City, Mexico

Carmen Sanchez-Soto

Affiliation Department of Biophysics, Institute of Cellular Physiology, National Autonomous University of México, Mexico City, Mexico

Victoria Godinez-Puig

Affiliation Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico

Gabriel Gutiérrez-Ospina

Affiliation Department of Cell Biology and Physiology, Biomedical Research Institute, National Autonomous University of México, Mexico City, Mexico

Marcia Hiriart

*To whom correspondence should be addressed. E-mail: mhiriart@ifc.unam.mx

Affiliation Department of Biophysics, Institute of Cellular Physiology, National Autonomous University of México, Mexico City, Mexico

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MH CA GG. Performed the experiments: MH CA CS VG. Analyzed the data: MH CA CS VG GG. Contributed reagents/materials/analysis tools: MH CA GG. Wrote the paper: MH CA GG.

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Glucose
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Insulin
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Insulin secretion
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Glucagon
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Enzyme-linked immunoassays
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Blood plasma
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Pancreas
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Blood sugar
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