About the Authors

Ryo Matoba

Affiliation Developmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

Hitoshi Niwa

Affiliation Laboratory of Pluripotent Cell Studies, RIKEN Center for Developmental Biology, Kobe, Japan

Shinji Masui

Affiliation Laboratory of Pluripotent Cell Studies, RIKEN Center for Developmental Biology, Kobe, Japan

Satoshi Ohtsuka

Affiliation Laboratory of Pluripotent Cell Studies, RIKEN Center for Developmental Biology, Kobe, Japan

Mark G. Carter

Affiliation Developmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

Alexei A. Sharov

Affiliation Developmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

Minoru S.H. Ko

To whom correspondence should be addressed. E-mail: kom@mail.nih.gov

Affiliation Developmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MK RM HN. Performed the experiments: MC RM HN SM SO. Analyzed the data: MK AS RM HN. Wrote the paper: MK RM