Canine Population Structure: Assessment and Impact of Intra-Breed Stratification on SNP-Based Association Studies

Pascale Quignon; Laetitia Herbin; Edouard Cadieu; Ewen F. Kirkness; Benoit Hédan; Dana S. Mosher; Francis Galibert; Catherine André; Elaine A. Ostrander; Christophe Hitte

doi:10.1371/journal.pone.0001324

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Open Access

Peer-reviewed

Research Article

Canine Population Structure: Assessment and Impact of Intra-Breed Stratification on SNP-Based Association Studies

Pascale Quignon,

Affiliation Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Laetitia Herbin,

Affiliation CNRS UMR6061 Génétique et Développement, Université de Rennes 1, IFR140, CS 34317, Rennes, France
⨯
Edouard Cadieu,

Affiliation Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Ewen F. Kirkness,

Affiliation The J Craig Venter Institute, Rockville, Maryland, United States of America
⨯
Benoit Hédan,

Affiliation CNRS UMR6061 Génétique et Développement, Université de Rennes 1, IFR140, CS 34317, Rennes, France
⨯
Dana S. Mosher,

Affiliation Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Francis Galibert,

Affiliation CNRS UMR6061 Génétique et Développement, Université de Rennes 1, IFR140, CS 34317, Rennes, France
⨯
Catherine André,

Affiliation CNRS UMR6061 Génétique et Développement, Université de Rennes 1, IFR140, CS 34317, Rennes, France
⨯
Elaine A. Ostrander ,

*To whom correspondence should be addressed. E-mail: eostrand@mail.nih.gov (EO); hitte@univ-rennes1.fr (CH)

Affiliation Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Christophe Hitte

*To whom correspondence should be addressed. E-mail: eostrand@mail.nih.gov (EO); hitte@univ-rennes1.fr (CH)

Affiliation CNRS UMR6061 Génétique et Développement, Université de Rennes 1, IFR140, CS 34317, Rennes, France
⨯

Canine Population Structure: Assessment and Impact of Intra-Breed Stratification on SNP-Based Association Studies

Pascale Quignon,
Laetitia Herbin,
Edouard Cadieu,
Ewen F. Kirkness,
Benoit Hédan,
Dana S. Mosher,
Francis Galibert,
Catherine André,
Elaine A. Ostrander,
Christophe Hitte

Published: December 19, 2007
https://doi.org/10.1371/journal.pone.0001324

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Why would this be?

Posted by asolove on 21 Dec 2007 at 00:58 GMT

one GR remaining as an outlier
http://plosone.org/article/info:doi/10.1371/journal.pone.0001324#article1.body1.sec2.sec6.p1

I'm certain the authors can explain, but I would like to know why.

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Canine Population Structure: Assessment and Impact of Intra-Breed Stratification on SNP-Based Association Studies

Canine Population Structure: Assessment and Impact of Intra-Breed Stratification on SNP-Based Association Studies

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Why would this be?

Posted by asolove on 21 Dec 2007 at 00:58 GMT