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Research Article

Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy

  • Jingqiu Chen equal contributor,

    equal contributor Contributed equally to this work with: Jingqiu Chen, Daniel Korostyshevsky

    Affiliation: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America

    X
  • Daniel Korostyshevsky equal contributor,

    equal contributor Contributed equally to this work with: Jingqiu Chen, Daniel Korostyshevsky

    Affiliation: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America

    X
  • Sean Lee,

    Affiliation: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America

    X
  • Ethan O. Perlstein mail

    eperlste@princeton.edu

    Affiliation: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America

    X
  • Published: April 18, 2012
  • DOI: 10.1371/journal.pone.0034024

Reader Comments (16)

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Media Coverage of This Article

Posted by PLoS_ONE_Group on 20 Apr 2012 at 21:28 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: Psych Central News
Title: “New Insight On How Antidepressants Work | Psych Central News”
http://psychcentral.com/n...

Publication: Eureka Alert
Title: “Yeast cell reaction to Zoloft suggests depression cause, drug target beyond serotonin”
http://www.eurekalert.org...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

RE: Media Coverage of This Article

PLoS_ONE_Group replied to PLoS_ONE_Group on 27 Apr 2012 at 21:30 GMT

Publication: Science News
Title: “Brain Not Required For Antidepressant To Act - Science News”
http://www.sciencenews.or...

Publication: Princeton University
Title: “Princeton University - Yeast cell reaction to Zoloft suggests alternative cause, drug target for depression”
http://www.princeton.edu/...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

Additional links to press coverage

eperlste replied to PLoS_ONE_Group on 04 May 2012 at 01:36 GMT

Publication: BioWorld

Title: "Simple Model Gives Insight Into SSRI's Cellular Effects"
http://www.bioworld.com/c...


Publication: Daily Princetonian

Title: "Zoloft has adverse effects on yeast cells"
http://www.dailyprinceton...

No competing interests declared.

RE: Additional links to press coverage

PLoS_ONE_Group replied to eperlste on 18 May 2012 at 22:09 GMT

Publication: Corante.com
Title: “Antidepressant Drugs and Cell Membranes. In the Pipeline:”
http://pipeline.corante.c...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

RE: RE: Additional links to press coverage

PLoS_ONE_Group replied to PLoS_ONE_Group on 24 Jul 2012 at 21:59 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: EveryONE PLoS ONE Community Blog
Title: “No Comment? | EveryONE”
http://blogs.plos.org/eve...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff