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closethere was an error in Fig.3B
Posted by zhenlinhu on 19 Sep 2014 at 03:07 GMT
We noted that there was an inadvertent error in Fig.3B, pertaining to the effect of baicalein (BE), at concentrations of 5, 10, and 20 μM, on the expression of FasL on both activated and naïve T lymphocytes. The data of Fig. 3B was obtained through the flow cytometry analysis of the percentage of FasL-positive cells in both activated T lymphocytes (with Con A stimulation) and naïve T lymphocytes (without Con A stimulation) after BE treatment. In reviewing the flow cytometry data displayed on Fig. 3B, we noted that two pair of dot plots purporting to show the percentage of FasL-positive cells under different conditions (“0 μM BE without Con A” vs. “5 μM BE without Con A” and “5 μM BE with Con A” vs. “10 μM BE with Con A”) are exactly same but the reported statistic values are different. After carefully comparing these data with our originally recorded flow cytometric analysis results, we realized that this is due to that the dot plot obtained under condition of “0 μM BE without Con A” was mistakenly used once again for the condition of “5 μM BE without Con A” and the dot plot obtained under condition of “5 μM BE with Con A” was mistakenly used once again for the condition of “10 μM BE with Con A” when Fig. 3B was configured. Since the mistakenly used dot plots look very similar to the correct ones, we had not noticed these dot plots have been used twice. But we had checked the statistic values presented in the dot plots with our original record, so the statistic values in the dot plots were presented correctly for the corresponding conditions. Therefore, the error should not substantially affect the conclusion drew from Fig.3. Nevertheless, we know such an error is not allowable in a scientific report. So we have submitted our correction request to PLOS ONE Journal Office. Before our correction being finally resolved, we would like to inform the readers of the error now. We regret the error that occurred while configuring this figure for this manuscript and accepts sole responsibility for this mistake.