Epithelial Mesenchymal Transition Is Required for Acquisition of Anoikis Resistance and Metastatic Potential in Adenoid Cystic Carcinoma

Jun Jia; Wei Zhang; Jian-Ying Liu; Gang Chen; Hui Liu; Hao-Yan Zhong; Bing Liu; Yu Cai; Jia-Li Zhang; Yi-Fang Zhao

doi:10.1371/journal.pone.0051549

Loading metrics

Open Access

Peer-reviewed

Research Article

Epithelial Mesenchymal Transition Is Required for Acquisition of Anoikis Resistance and Metastatic Potential in Adenoid Cystic Carcinoma

Jun Jia ,

Contributed equally to this work with: Jun Jia, Wei Zhang

Affiliations The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, China
⨯
Wei Zhang ,

Contributed equally to this work with: Jun Jia, Wei Zhang

Affiliations The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, China
⨯
Jian-Ying Liu,

Affiliation The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China
⨯
Gang Chen,

Affiliations The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, China
⨯
Hui Liu,

Affiliation The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China
⨯
Hao-Yan Zhong,

Affiliations The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, China
⨯
Bing Liu,

Affiliation Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, China
⨯
Yu Cai,

Affiliations The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, China
⨯
Jia-Li Zhang,

Affiliations The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China, Department of Pathology, School and Hospital of Stomatology, Wuhan University, Wuhan, China
⨯
Yi-Fang Zhao

* E-mail: yifang@whuss.com

Affiliations The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, China
⨯

Epithelial Mesenchymal Transition Is Required for Acquisition of Anoikis Resistance and Metastatic Potential in Adenoid Cystic Carcinoma

Jun Jia,
Wei Zhang,
Jian-Ying Liu,
Gang Chen,
Hui Liu,
Hao-Yan Zhong,
Bing Liu,
Yu Cai,
Jia-Li Zhang,
Yi-Fang Zhao

Published: December 14, 2012
https://doi.org/10.1371/journal.pone.0051549

Reader Comments

Post a new comment on this article

ACC2 and ACCM cells are HeLa cells

Posted by Osamu-OHNS on 19 May 2014 at 21:10 GMT

ACC2 and ACCM were determined to be HeLa cervical cancer cells. The study was unfortunately unrelated to adenoid cystic carcinoma.

No competing interests declared.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Metastasis
Is the Subject Area "Metastasis" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Small interfering RNA
Is the Subject Area "Small interfering RNA" applicable to this article?

Thanks for your feedback.
Slugs
Is the Subject Area "Slugs" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Vimentin
Is the Subject Area "Vimentin" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Hyperexpression techniques
Is the Subject Area "Hyperexpression techniques" applicable to this article?

Thanks for your feedback.

Epithelial Mesenchymal Transition Is Required for Acquisition of Anoikis Resistance and Metastatic Potential in Adenoid Cystic Carcinoma

Epithelial Mesenchymal Transition Is Required for Acquisition of Anoikis Resistance and Metastatic Potential in Adenoid Cystic Carcinoma

Reader Comments

Post Your Discussion Comment

Why should this posting be reviewed?

Thank You!

ACC2 and ACCM cells are HeLa cells

Posted by Osamu-OHNS on 19 May 2014 at 21:10 GMT